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KMID : 0882420120830060823
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Korean Journal of Medicine
2012 Volume.83 No. 6 p.823 ~ p.827
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Platelet Dysfunction in a Patient with Multiple Myeloma: A Case Report with a Literature Review
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Na Soo-Young
Park Jin-Wook
Choi Jun-Seok
Lee Dae-Ho
Chi Hyun-Sook
Lee Jung-Shin
Suh Chul-Won
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Abstract
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Multiple myeloma is a monoclonal plasma cell proliferation disorder with various symptoms and signs caused by paraproteinemias. Among these signs, a bleeding tendency is one of the major fatal causes. However, significant severe bleeding is rare in most cases. In this study, we report a case of multiple myeloma in a patient who had a severe recurrent bleeding tendency due to platelet dysfunction caused by paraproteins. After being treated with therapeutic plasma exchange and chemotherapy, the patient’s monoclonal protein level decreased and the bleeding stopped.
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KEYWORD
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Multiple myeloma, Paraproteinemias, Hemostatic disorders, Platelet function tests, Plasmapheresis
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